Paper May 2024
of Saccharomyces cerevisiae is that aneuploidy—an imbalance in chromosome copy numbers—is frequent 1 , 2 (around 20%), which seems to contradict the substantial fitness costs and transient nature of aneuploidy [...] engineered in the laboratory 3 , 4 , 5 . Here we generate a proteomic resource and merge it with genomic 1 and transcriptomic 6 data for 796 euploid and aneuploid natural isolates. We find that natural and [...] into complex biological processes. https://doi.org/10.1038/s41586-024-07442-9 © J.Muenzner et al. Fig. 1: High-throughput proteomics pipeline and assembly of a cross-omics dataset for studying aneuploidy in …
